mouse anti-nr2a Search Results


mouse monoclonal anti-nr2a  (Becton Dickinson)
90
Becton Dickinson mouse monoclonal anti-nr2a
A) For purposes of this experiment, prefrontal cortex was defined as cortical tissue anterior to the caudate-putamen (brain shown from above; dissection indicated by perforated black line). B) Ventral hippocampus was defined as the lower 40-45% (hippocampus shown in the caudal plane and dissection indicated by the perforated black line). In prefrontal cortex, Pde11a knockout (KO) mice show C) increased expression of the NR1 (WT, n=36, KO, n=37, F(1,69)=4.67, P=0.034) and D) <t>NR2A</t> subunits (n=43/genotype, failed normality, Rank Sum Test, T(43,43)=1610, P=0.025) relative to wild-type littermates, but E) no change in expression of the NR2B subunit (WT, n=39, KO, n=40). In VHIPP, there was no difference between Pde11a knockout mice vs. wild-type littermates in terms of F) NR1 (n=17/genotype), G) NR2A (WT, n=30, KO, n=31), nor H) NR2B (WT, n=18, KO, n=19). *vs WT, P=0.034-0.025. See Figure S7 for images of full blots. Brightness and contrast of blot images adjusted for graphical clarity. Data plotted as means ±SEMs. Images in panels A and B from Allen Institute for Brain Sciences http://connectivity.brain-map.org./3d-viewer.
Mouse Monoclonal Anti Nr2a, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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A) For purposes of this experiment, prefrontal cortex was defined as cortical tissue anterior to the caudate-putamen (brain shown from above; dissection indicated by perforated black line). B) Ventral hippocampus was defined as the lower 40-45% (hippocampus shown in the caudal plane and dissection indicated by the perforated black line). In prefrontal cortex, Pde11a knockout (KO) mice show C) increased expression of the NR1 (WT, n=36, KO, n=37, F(1,69)=4.67, P=0.034) and D) NR2A subunits (n=43/genotype, failed normality, Rank Sum Test, T(43,43)=1610, P=0.025) relative to wild-type littermates, but E) no change in expression of the NR2B subunit (WT, n=39, KO, n=40). In VHIPP, there was no difference between Pde11a knockout mice vs. wild-type littermates in terms of F) NR1 (n=17/genotype), G) NR2A (WT, n=30, KO, n=31), nor H) NR2B (WT, n=18, KO, n=19). *vs WT, P=0.034-0.025. See Figure S7 for images of full blots. Brightness and contrast of blot images adjusted for graphical clarity. Data plotted as means ±SEMs. Images in panels A and B from Allen Institute for Brain Sciences http://connectivity.brain-map.org./3d-viewer.

Journal: Current biology : CB

Article Title: Loss of function of phosphodiesterase 11A4 shows that recent and remote long term memories can be uncoupled

doi: 10.1016/j.cub.2019.06.018

Figure Lengend Snippet: A) For purposes of this experiment, prefrontal cortex was defined as cortical tissue anterior to the caudate-putamen (brain shown from above; dissection indicated by perforated black line). B) Ventral hippocampus was defined as the lower 40-45% (hippocampus shown in the caudal plane and dissection indicated by the perforated black line). In prefrontal cortex, Pde11a knockout (KO) mice show C) increased expression of the NR1 (WT, n=36, KO, n=37, F(1,69)=4.67, P=0.034) and D) NR2A subunits (n=43/genotype, failed normality, Rank Sum Test, T(43,43)=1610, P=0.025) relative to wild-type littermates, but E) no change in expression of the NR2B subunit (WT, n=39, KO, n=40). In VHIPP, there was no difference between Pde11a knockout mice vs. wild-type littermates in terms of F) NR1 (n=17/genotype), G) NR2A (WT, n=30, KO, n=31), nor H) NR2B (WT, n=18, KO, n=19). *vs WT, P=0.034-0.025. See Figure S7 for images of full blots. Brightness and contrast of blot images adjusted for graphical clarity. Data plotted as means ±SEMs. Images in panels A and B from Allen Institute for Brain Sciences http://connectivity.brain-map.org./3d-viewer.

Article Snippet: Mouse monoclonal anit-NR2A , BD Transduction , Cat#: 612286; RRID:AB_399603.

Techniques: Dissection, Knock-Out, Expressing

KEY RESOURCES TABLE

Journal: Current biology : CB

Article Title: Loss of function of phosphodiesterase 11A4 shows that recent and remote long term memories can be uncoupled

doi: 10.1016/j.cub.2019.06.018

Figure Lengend Snippet: KEY RESOURCES TABLE

Article Snippet: Mouse monoclonal anit-NR2A , BD Transduction , Cat#: 612286; RRID:AB_399603.

Techniques: Transduction, Plasmid Preparation, Recombinant, Enzyme-linked Immunosorbent Assay, Software, Injection